1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the cure of a number of myeloma. Its synthesis or research is crucial for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets specific sorts of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is important for optimizing the creation system and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast most cancers, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the procedure of breast cancer. Various intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is Pemetrexed Intermediate involved in the synthesis of adamantane derivatives, that have various applications, such as antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: CAS NO. 848133-35-7 A precursor within the synthesis of canagliflozin, a medication used to deal with style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).